Exploiting vita-PAMPs in vaccines

Trends in adjuvant development for vaccines: DAMPs and PAMPs as potential new adjuvants.

Aluminum salts have been widely used in vaccine formulations and, after their introduction more than 80 years ago, only few vaccine formulations using new adjuvants were developed in the last two decades. Recent advances in the understanding of how innate mechanisms influence the adaptive immunity opened up the possibility for the development of new adjuvants in a more rational design. The purp...

Vita Summary

Sweeten PAMPs: Role of Sugar Complexed PAMPs in Innate Immunity and Vaccine Biology

Innate sensors play a critical role in the early innate immune responses to invading pathogens through sensing of diverse biochemical signatures also known as pathogen associated molecular patterns (PAMPs). These biochemical signatures primarily consist of a major family of biomolecules such as proteins, lipids, nitrogen bases, and sugar and its complexes, which are distinct from host molecules...

Vita: Friedrich Wilhelm Wiener

We report on the life and work of F. Wiener, whom we confused with N. Wiener in a previous article.

Curriculum Vita of James

[1] Professor of Mathematics; University of Vermont, 1999-present. [1] Visiting Associate Professor of Mathematics; Rutgers University (New Brunswick, New Jersey) [on sabbatical from UVM], 1992-1993. [2] Associate Professor of Mathematics; University of Vermont, 1991-1999. [3] Assistant Professor of Mathematics; University of Vermont, 1986-1991. [4] Van Vleck Assistant Professor; University of ...